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Eight studies found sex-based differences in possible predictors of long-term outcome prolonged epileptiform EEG runs and the presence of eye closure sensitivity, both more frequent in women, were factors possibly linked to a poorer prognosis, as were praxis induction and generalized EEG asymmetric changes, which instead were more common in men. Valproate use, more frequent in men, was associated with a better outcome. Most studies do not highlight sex differences in JME prognosis. However, some sex specificities do emerge, especially w
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