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Background Cystic thyroid lesions represent one of the most common causes of unsatisfactory fine-needle aspiration sampling. Thus, it is important to access the maximum number of follicular cells from cystic fluid in order to reduce unsatisfactory rates. We compared the traditional method of smearing with an alternative one. Methods For each thyroid nodule, two smears were collected. Each smear was prepared using a distinct approach either using the traditional technique or the alternative. Clinical data were taken from cytopathological
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