https://www.selleckchem.com/pr....oducts/Roscovitine.h
Radiation therapy increases the risk of secondary malignancy and morbidity in cancer survivors. The role of obesity and exercise training in modulating this risk is not well-understood. As such, we used a preclinical model of radiation-induced malignancy to investigate whether diet-induced obesity and/or endurance exercise training altered life-long survival, cancer incidence, and morbidity. Male CBA mice were randomly divided into control diet/sedentary group (CTRL/SED), high fat diet (45% fat)/sedentary group (HFD/SED), control di
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