https://www.selleckchem.com/pr....oducts/cx-4945-silmi
Glioma, the most frequent primary tumor of the central nervous system, has poor prognosis. The epidermal growth factor receptor (EGFR) pathway and angiogenesis play important roles in glioma growth, invasion, and recurrence. The present study aimed to use proteomic methods to probe into the role of the EGF-EGFR-angiogenesis axis in the tumorigenesis of glioma and access the therapeutic efficacy of selumetinib on glioma. Proteomic profiling was used to characterize 200 paired EGFR-positive and EGFR-negative glioma tissues o
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