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Here we discuss how HNSCC provides a unique model to study the STING pathway in the context of viral induced tumor type as well as recent advances in our understanding of this pathway in HSNCC.The survival benefit derived from sorafenib treatment for patients with hepatocellular carcinoma (HCC) is modest due to acquired resistance. Targeting cancer stem cells (CSC) is a possible way to reverse drug resistance, however, inhibitors that specifically target liver CSCs are limited. In this study, we established two sorafenib-resistant, patien
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