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tonia (EU48695) and Karolinska Institute. Authors do not have any conflict of interest. We aimed to develop a gene expression-based prognostic signature for isocitrate dehydrogenase (IDH) wild-type glioblastoma using clinical trial datasets representative of glioblastoma clinical trial populations. Samples were collected from newly diagnosed patients with IDH wild-type glioblastoma in the ARTE, TAMIGA, EORTC 26101 (referred to as "ATE", AVAglio, and GLARIUS trials, or treated at UCLA. Transcriptional profiling was achieved with the NanoS
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