https://www.selleckchem.com/pr....oducts/cremophor-el.
4 mM). RESULTS We found that palmitate alone induced the activation of the nucleotide-binding oligomerization domain-like receptor (NLR) Family Pyrin Domain Containing 3 (NLRP3) inflammasome in placental macrophages, which was associated with increased interleukin 1 beta release and an increase in apoptotic cell death. Glucose and insulin neither provoked these effects nor augmented the impact of palmitate itself. DISCUSSION Our findings confirm an impact of saturated fat on placental macrophage immune activation and could be relev
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