https://www.selleckchem.com/pr....oducts/Temsirolimus.
We set out to reprogram adult somatic oral epithelial keratinocytes into pluripotent cells for regenerative dentistry. Immortalized murine oral keratinocyte cell (IMOK) line raised from adult mouse mucosa were cultured in vitro in our studies. Adult murine oral epithelial keratinocytes were chronically treated with TGF-β1 in vitro, and the expression of Oct4, Nanog, Sox2 and Nestin, as well as specific homeobox Gata and Pax gene family members were investigated. We documented the induction of stem factors linked with pluripotency a
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