https://www.selleckchem.com/pr....oducts/ganetespib-st
Competitive transplantation of marrow cells into runx1 mutants revealed a stem cell frequency similar to that of murine marrow cells, which demonstrates the utility of this model for quantifying HSC function. The streamlined approach and robustness of this assay will help broaden its feasibility for future high-throughput transplantation experiments in zebrafish and will enable further novel discoveries in the biology of HSCs.BCR-ABL, an oncogenic fusion gene, plays a central role in the pathogenesis of chronic myeloid leuke
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