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Patients in the long-course CRT group reported more skin toxicity after radiotherapy (p=0.04. No differences were observed in late toxicity. In the long-course CRT group, a significantly higher cCR rate was observed (p=0.029); however, there was no difference in the pCR rate (p=0.66). The treatment of RRC patients with re-irradiation is comparable to treatment with long-course CRT regarding toxicity and oncological outcomes. In the reCRT group, less cCR was observed, although there was no difference in pCR. The findings in this study
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