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A total of 10 studies comprising 1,820 cases had been within the current meta-analysis. The following elements were identified as predictors of unresponsiveness Age (≥60 years), sex, absolute neutrophil count, extent of this condition, paroxysmal nocturnal hemoglobinuria clone, human leukocyte antigen (HLA)-DR2 and cytogenetic abnormalities (CAs). Among these aspects, just age (≥60 years) [odds ratio (OR)=1.65], HLA-DR2 negativity (OR=2.72) and CAs (OR=1.93) displayed a statistically significant connectio
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