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But, whether GSS drive back sepsis-induced EC injury and release of inflammatory mediators is not determined. In this study, we unearthed that GSS not merely downregulated the levels of TNF-α and IL-6 into the lung and serum of mice in vivo but additionally inhibited the expression and secretion of TNF-α and IL-6 in ECs. Significantly, we additionally unearthed that GSS blocked LPS-induced TNF-α and IL-6 expression in ECs via the Myd88/NF-κB signaling path. Taken collectivel
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