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The purpose of this study was to investigate the regulatory mechanism of ε-PL on Shewanella putrefaciens. Proteomics analysis of inhibitory effect of ε-PL against S. putrefaciens were performed by label-free quantitative assay based on high-resolution mass spectrometry (MS). Quantification of 2206 proteins was obtained with high confidence, and a total of 36 differentially expressed proteins (DEPs), with 10 and 26 proteins showing up- and down-regulation, respectively, were identified. Upon Go functional enrichment, 11, 5, and 8 specific
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