https://www.selleckchem.com/pr....oducts/pnd-1186-vs-4
Hormonal reproductive factors have been suggested to play an important role in the etiology of rheumatoid arthritis (RA), an autoimmune inflammatory disorder affecting primarily women. We conducted a two-sample Mendelian randomization (MR) study examining three relevant exposures, age at menarche (AAM), age at natural menopause (ANM), and age at first birth (AF with the risk of RA. We collected summary statistics from the hitherto largest GWAS conducted in AAM (N = 329,345), ANM (N = 69,36, AFB (N = 251,151), and RA (N = 1
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