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The diagnosis of spinal cord infarction should always be kept in mind. A case report with a review of the current literature concerning cutaneous necrosis has occasionally been reported in interferon therapy. We report a 19-year-old woman diagnosed multiple sclerosis for three years. She selfinjected the standard dose of recombinant interferonβ-1a (12 million units) subcutaneously three times a week. Severe necrotizing cutaneous reactions over abdomen Happened and she must receive parental antibiotics and surgical debridement. Our obser
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