https://www.selleckchem.com/pr....oducts/irak4-in-4.ht
Men with obesity tend to be insulin resistant and often have low-normal testosterone concentrations. We conducted a clinical trial aimed to evaluate potential therapeutic strategies for low testosterone in men with obesity. We did a 1-year, parallel, randomized, double-blind, placebo-controlled trial, where we evaluated the independent and combined effects of metformin and testosterone in 106 men with obesity, aged 18-50years, who had low levels of testosterone and no diabetes mellitus. The primary outcome was change in insulin resis
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