https://www.selleckchem.com/pr....oducts/anlotinib-al3
We report, herein, a palladium-catalysed cascade comprising carbopalladation, 1,4-Pd-migration and C(sp 2 )-C(sp 2 ) bond formation to construct a variety of bis-heterocyclic frameworks in a single operational step. The methodology provides a direct approach to introduce an oxadiazole core at a remote location without any functional group obligation, with moderate to good yields.Infections from antibiotic-resistant Staphylococcus aureus and Pseudomonas aeruginosa are a serious threat because reduced antibiotic efficacy complica
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