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at individuals reporting emotional distress and maladaptive cognitive appraisals of pain may benefit less from placebo effects. Early Years' Settings (EYSs) provide childcare and education for children 0-5 years old. They remained fully open in England during the third National lockdown when other educational settings were only open for selected children. EYSs are generally considered to be low-risk settings for transmission of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2). An observational study describing a large outbre
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