https://www.selleckchem.com/products/S31-201.html
Cerebrovascular pathologies including cerebral amyloid angiopathy (CAA) and blood-brain barrier (BB dysregulation are prominent features in the majority of Alzheimer's disease (AD) cases. We performed neuropathologic and biochemical studies on a large, neuropathologically confirmed human AD cohort (N = 469). Amounts of endothelial tight junction proteins claudin-5 (CLDN5) and occludin (OCLN), and major AD-related molecules (amyloid beta [Aβ40], Aβ42, tau, p-tau, and apolipoprotein E) in the temporal cortex were assessed by ELISA. High
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