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Prevention campaigns that increase knowledge, promote positive attitudes, change perception of susceptibility, and address barriers may result in higher HPV vaccination rates among males in college/university settings.Lung cancer is the leading cause of cancer-related death globally. Ubiquitin modification plays a crucial role in regulation of gene expression, and is closely related to cancer pathogenesis. The aim of our study is to demystify the role and action mechanism of HECT, C2 and WW domain containing E3 ubiquitin protein ligase
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