https://www.selleckchem.com/pr....oducts/tak-243-mln24
Characterization of N,N'-substituted ureas was found to be challenging by NMR, particularly N-di and tri-alkylated ureas because of the absence of adjacent protons. In the present study, electrospray ionization tandem mass spectrometry has been used to differentiate positional isomeric pairs and to characterize a series of N,N'-substituted ureas, as these compounds have significant importance for drug discovery. Additionally, urea is an essential functionality in several bioactive compounds as well as a variety of clinically appr
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