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The β diversity showed that the MRA of cyanobacteria was higher in the CRSwNP group than the control group before the operation（P less then 0.05）, but significantly decreased（P less then 0.05） to be close to the control group at 3 months postoperatively. ②Comparing the microbiome with clinical factors and prognosis, we found that both the Lund-Kennedy scores and the history of asthma were positively correlated with the MRA of pseudomonas（r=0.397, P=0.012; r=0.420, P=0.008）. Campylobacter was negatively correlated with improvement of SNOT-
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