https://www.selleckchem.com/pr....oducts/alflutinib-as
In this review, we briefly discuss the structure and regulation of R-Ras proteins and our current understanding of the signaling pathways that they regulate. We consider the phenotype of NS patients and the implications this has for R-Ras subfamily functions. We then turn to recent discoveries regarding physiological and pathologic R-Ras functions in key organ systems. We conclude by discussing how R-Ras signaling is dysregulated in cancers and mechanisms by which this may promote neoplasia.The Hedgehog (Hh) family o
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