https://www.selleckchem.com/pr....oducts/trilaciclib.h
These epitopes could activate and generate epitope-specific T cells in vitro, and those activated T cells showed cytolytic activity toward target cells. Meanwhile, n-Sp1 epitope variant 5LF significantly decreased the proportion of specific T-cell activation; n-Sp1 epitope 8LV variant showed significantly reduced binding to HLA-A*0201 and decreased proportion of n-Sp1-specific CD8+ T cell, which potentially contributes to the immune escape of SARS-CoV-2. Our data indicate that the variation of a dominant epitope will cause t
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