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In addition, depletion of DHX9 reduced cell cycle progression from G1 to S-phase in mouse fibroblasts. The data suggest that DHX9-CIZ1 are required for efficient cell cycle progression at the G1/S transition and that nucleolar recruitment is integral to their mechanism of action.Understanding past climate variability is critical to informing debate of likely impacts of global warming on weather and climate, and water resources. Here we present a near annual resolution reconstruction of climate developed from a speleothem that spans the Eem
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