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We confirmed that the yield angle identifies the yield stress for the thickened liquid via the DDE using the simplified inclined plane test with discrete inclination angles.The control of nutrient availability is critical to large-scale manufacturing of biotherapeutics. However, the quantification of proteinogenic amino acids is time-consuming and thus is difficult to implement for real-time in situ bioprocess control. Genome-scale metabolic models describe the metabolic conversion from media nutrients to proliferation and recombinant p
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