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To investigate the effect of natural crosslinkers proanthocyanidin, genipin and glutaraldehyde on shear bond strength at the composite resin-dentin interface . The in-vitro study was conducted at the Postgraduate Medical Institute, Lahore, Pakistan, from June to September 2018. Exposed dentin surfaces of extracted teeth were conditioned and randomly divided into proanthocyanidin, genipin, glutaraldehyde and control groups according to the type of surface treatment. The dentin surfaces were treated with 6.5% of primers proanthocyanidin,
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