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The anticancer effect of (2) has additionally been studied in an EAC (Ehrlich Ascites Carcinoma) mouse design. Considerably, the activity of the complex was more pronounced in vivo, with removal of the cancer tumors burden at doses that lead to just low levels of hepatotoxicity and nephrotoxicity. An apoptosis method ended up being determined by the observation of increased Bax and caspase 3 and reduced Bcl2 expression. Also, (2) decreased oxidative anxiety and increas
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