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42; 95% CI 1.16-1.75), chronic kidney disease (OR 1.35; 95% CI 1.08-1.68), and length of hospital stay (per day) (OR 1.03; 95% CI 1.02-1.04). Persistent postoperative opioid use after cardiac surgery affects at least one in 20 patients. The identification of risk factors, such as female sex, smoking, alcohol use, congestive cardiac failure, diabetes mellitus, chronic lung disease, chronic kidney disease, and length of hospital stay, should help target interventions aimed at decreasing its prevalence. Persistent postoperative opioid use
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