https://www.selleckchem.com/pr....oducts/compound-3i.h
However, CD146 did not affect the adhesion between OS and endothelium, nor did co-culture of both sides affect the CD146 expression. Similarly, the proliferation, migration and CD146 expression of MG63 remained unchanged after many cycles of migration itself, as did its co-culture with 143B for expressing CD146. In addition, we also showed that high glucose promoted the expression of CD146 in OS, while hypoxia had the opposite effect. These findings demonstrate that CD146 promotes OS progression by mediating pro-tumoral and angiogen
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