https://www.selleckchem.com/products/AZ-960.html
Rats that received LPS treatment exhibited high levels of lung wet/dry ratio, alkaline phosphatase, lactate dehydrogenase, BALF polymorphonuclear leukocytes count, inflammatory cytokines, and oxidative stress. Meanwhile, LPS also resulted in severe interstitial edema and inflammatory cell infiltration. Interestingly, telmisartan by oral administration markedly ameliorated the adverse effects of pneumonia in rats caused by LPS. In addition, western blotting further revealed that telmisartan could activate PPARγ and repress NF-κB (p65). Te
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