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016). The use of rapid rewarming did not correlate with tissue salvage (P=0.112). Early use of thrombolytics had a positive impact on tissue salvage (P=0.003). Thrombolytics were given 1.2 hours earlier in direct admit patients (P=0.029), however there was no difference in tissue salvage rates between the groups (P=0.127). Efforts should focus on larger scale study to further assess the effectiveness of rapid rewarming. Although rapid rewarming did not significantly impact tissue salvage in this study, we continue to recommend its use o
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