https://www.selleckchem.com/
Furthermore, miR-16 suppressed U87 migration in wound-healing assay and invasion across transwell membrane in vitro. In an orthotopic tumor model, overexpression of miR-16 inhibited tumor growth in vivo was accompanied with reduction in cyclin D1 and WIP1 expression in the xenografts. CD31 expression in miR-16-overexpressed xenografts was also decreased. #link# The determined microvessel density of the miR-16 overexpression group was significantly lower than those groups treated with vehicle and empty vector. MicroRNA-16 exhibits inhibitory effects of gliob
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