https://www.selleckchem.com/pr....oducts/eapb02303.htm
When cells were infected with , the intracellular recovery of CFUs showed up to a 0.66 log reduction in cells exposed to cigarette smoke extract because of a potential impairment in the phagocytosis. Macrophages treated with drugs showed up to a 2.55 log reduction in the intracellular load burden compared with non-treated ones. Despite poor treatment outcome on TB smoker patients, minimal inhibitory concentration of rifampicin increased only 2-fold in exposed to cigarette smoke. Smoking interferes with tuberculosis treatment impairing
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