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Pyoderma gangrenosum (PG) is a chronic inflammatory disease in the rare group of neutrophilic dermatoses. PG is extremely rare in the breast, and most of the women who develop PG after surgery, such as mammoplasty (1,2). A case of a male patient with PG who developed IgA gammopathy without breast trauma or surgery is presented to emphasize the sparing of the areola and nipple. This article is protected by copyright. All rights reserved.A subset of presynaptic glutamatergic vesicles in the brain co-releases zinc (Zn2+ ) with glutamate in
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