https://www.selleckchem.com/pr....oducts/afuresertib-g
BARX2 expression was negatively correlated with DNMT (a marker for DNA methylation) expression in the gastric tissues. The BARX2 promoter fragment was hypermethylated in the GC cell lines. Overexpression of BARX2 significantly inhibited GC cell proliferation, clonal formation, and migration. Stable BARX2 transfection inhibited tumor formation in xenograft mice, which was correlated with decreased expression of E‑cadherin, proliferation markers, and matrix metalloproteinases. In conclusion, BARX2 expression is aberrantly r
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