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We validated the selected model by reproducing results from two previous clinical studies. The selected model accurately simulates the physiological effects of moderate exercise on glucose dynamics in individuals with type 1 diabetes. This work offers an important tool to develop strategies for exercise management with the artificial pancreas.Upon discovery of the first archaeal species in the 1970s, life has been subdivided into three domains Eukarya, Archaea, and Bacteria. However, the organization of the three-domain tree of life has
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