https://www.selleckchem.com/pr....oducts/2-3-butanedio
Anhedonia, the loss of pleasure in previously rewarding activities, is a prominent feature of major depressive disorder (MDD) and often resistant to first-line antidepressant treatment. A paucity of translatable cross-species tasks to assess subdomains of anhedonia, including reward learning, presents a major obstacle to the development of effective therapeutics. One assay of reward learning characterized by orderly behavioral and pharmacological findings in both humans and rats is the Probabilistic Reward Task (PRT).
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