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Among they were the bifunctional course A PBPs, which tend to be both glycosyltransferases and transpeptidases, and monofunctional class B PBPs with only transpeptidase activity. Recently, nonetheless, it had been founded that the monofunctional class B PBPs interact with transmembrane glycosyltransferases (FtsW and RodA) through the form, elongation, unit, and sporulation (SEDS) family members in order to make up the core peptidoglycan-synthesizing machineries within the pneumoco
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