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How Does ADHD Medication Work? The drugs help reduce ADHD symptoms by increasing levels of Dopamine and Noradrenaline. Both are chemicals that transmit messages between brain cells. The most frequently prescribed stimulants are methylphenidate and the atomoxetine. Finding and dosage is often a trial and error process. Your doctor's communication with you should be open and honest. Stimulants The stimulant medications prescribed to treat ADHD increase levels of dopamine and Naradrenaline. The exact mechanism behind this is not clear but the result is
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