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01, p=0.01 and p less then 0.01, respectively). The largest increase was observed for GFAP with the post-injury median concentration increasing nearly seven-fold. The use of these TBI biomarkers for diagnosing and managing TON may be helpful for non-ophthalmologists in particular in diagnosing this condition. In addition, the potential utility of these biomarkers for diagnosing other optic nerve and/or retinal pathologies should also be evaluated.Introduction. Warning signs play a very important role in safeguarding life and property in
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