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As such, targeting both microglial and global type-I IFN signalling presents as a novel therapeutic strategy for AD management.In the central nervous system (CNS), γ-aminobutyric acid A (GABAA) receptors mediate two types of inhibitory effects. Phasic inhibition involves the activation of synaptic GABAA receptors, and tonic inhibition is mediated by extrasynaptic GABAA receptors. GABAA receptors are important regulators of neuronal activity and are involved in a range of neurological disorders. In this study, we conducted sIPSCs recordin
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