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5 (sensitivity 0.84; specificity 0.70; area under the curve = 0.842). Length of stay (median 9.5 vs 5 days; = .0002) and initiation (53% vs. 33%; = .018) and duration of pharmacologic treatment (median 11 vs 7 days; = .0042), as well as length of stay for infants who were pharmacologically treated (median 15 vs 10 days; = .0002), were significantly reduced with ESC-based management after adjustment for covariates. The ESC approach meaningfully correlates with the M-FNASS to detect NOWS. Management with the ESC approach continues to be a
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