https://www.selleckchem.com/btk.html
05). There was no effect on ovulation or fertilization rates. However, blastocysts from imatinib-treated females had fewer total cells (P less then 0.05) and a significant shift from inner cell mass to increased trophectoderm cells. CONCLUSION This pilot study indicates that long-term TKI treatments may have significant impact on ovarian reserve and embryo developmental capacity. More studies are needed in other model systems to determine the long-term impact of TKIs in patients. Knowing the potential effects of chemotherapeutics on reproductive o
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