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To determine whether targeting a mean arterial pressure of 90 mmHg (MAP9 would yield improved cerebral blood flow and less ischaemia compared to MAP 60 mmHg (MAP6 with and without targeted temperature management at 33 °C (TTM33) in a porcine post-cardiac arrest model. After 10 min of cardiac arrest, 41 swine of either sex were resuscitated until return of spontaneous circulation (ROSC). They were randomised to TTM33 or no-TTM, and MAP60 or MAP90; yielding four groups. Temperatures were managed with intravasal cooling and blood pres
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