https://www.selleckchem.com/pr....oducts/nsc-663284.ht
Iron-sulfur clusters (ISCs) are highly conserved moieties embedded into numerous crucial proteins in almost all bacteria, plants and mammals. As such, ISC biosynthesis is critical to cellular function. The pathway was first characterized in bacteria by the late 1990s, and over the subsequent 20 years there has been increasing understanding of its components in humans. Defects in ISC pathway components are now associated with many different human disease states, such as Friedreich ataxia and ISCU myopathy. Whilst the disorders have va
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