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22, 95% PI 0.15-0.3. The association of pCR with improved EFS was similar among patients who received subsequent adjuvant chemotherapy (HR 0.36, 95% PI 0.19-0.67) and those without adjuvant chemotherapy (HR 0.36, 95% PI 0.27-0.54), with no significant difference between the two groups (p = 0.6. INTERPRETATION Achieving pCR following NAT is associated with significantly better EFS and OS, particularly for triple negative and HER2+ breast cancer. The similar outcomes with or without adjuvant chemotherapy in patients who attain pCR li
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