https://www.selleckchem.com/pr....oducts/bibo-3304-tri
Risk of bias for each trial was assessed, and the random-effect model was used to pool summary effect across trials. Results In all 30 eligible RCTs, the risk of bias for randomization was low except for one study. The pooled standardized mean difference (SMD) for depression and anxiety were 1.33 (95%CI -1.42 to -0.68) and 1.25 (95% CI -1.55 to -0.96), respectively. Conclusion This study suggests that psychological interventions are highly effective in reducing depression and anxiety in Iranian patients with chronic p
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