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The changed lung microbiota showed significant correlations with lung metabolites. The amount of fumaric acid adversely correlated with the relative abundance of Ruminococcaceae, Enterobacteriaceae, and Pseudomonadaceae. These outcomes revealed that PM2.5 exposure not merely significantly changed the lung microbiome composition but also perturbed a number of metabolites associated with diverse metabolic pathways. This research gets better our understanding of the device of lung in
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