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3±0.5 vs. 1.9±1.1cm; p=0.008 and volume 0.30±0.20 vs. 1.2±1.1cm ; p0.001), less heavy (567±282 vs. 1470±1374mg; p=0.03 and were localized more frequently in upper situation (65% vs. 16%; p0.001) than patients with positive scanning. In the multivariate analysis an independent association between negative Tc-MIBI scanning and size of removed adenoma ≤1cm (OR 5.77; 95% CI 1.46-22.71) and upper adenoma localization were observed (OR 8.05; 95% IC 2.22-29.16). One in four patients studied for PHPT had a negative Tc-MIBI scanning an
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